THE LEE LAB
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​Ecology meets genomics: decoding how microbial communities shape the health of hosts and environments.

Our research is grounded in ecological theory and microbiology, with applications that promote the health of both environments and microbial-host systems. We rely heavily on bioinformatics and molecular techniques to elucidate how microbial populations contribute to the well-being of their hosts.

Our work centers around three major themes:
  1. Computational genomics - using bioinformatic approaches to study microbial populations and their genomes following ecological disturbances
  2. Targeted culturing - isolating microbial populations of interest for functional characterization
  3. Ecological mechanisms - determining the drivers of microbial succession and the interplay between microbiomes and their hosts or environment

​Additionally, our work currently incorporates the following systems:
  1. Andropogon gerardii
  2. Arabidopsis thaliana
  3. Plant protoplasts
  4. HeLa cervical cancer cells
  5. Caco-2 cells - colorectal adenocarcinoma or colon tumor cells
  6. Colonoids - colon organoids derived from a healthy patient
  7. Various mouse models
  8. Single-cell isolates from both the human gut and plant rhizosphere

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In collaboration with colleagues across disciplines, we synthesize multi-omic data with environmental and biochemical insights to understand how microbial populations are critical to the health of both environmental and host systems — especially in the context of perturbation and recovery.
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The Lee Lab at Kansas State University


  • RESEARCH
  • PUBLICATIONS
  • PEOPLE
  • WE ARE HIRING!
  • BLOG